Merja Kokki Selected Research

Buprenorphine (Subutex)

12/2023	Buprenorphine plasma and cerebrospinal fluid concentrations in osteoarthritis patients during low-dose transdermal patch dosing.
11/2022	Central nervous system distribution of buprenorphine in pregnant sheep, fetuses and newborn lambs after continuous transdermal and single subcutaneous extended-release dosing.
10/2021	MATERNAL AND FETAL BUPRENORPHINE PHARMACOKINETICS IN PREGNANT SHEEP DURING TRANSDERMAL PATCH DOSING: Buprenorphine pharmacokinetics in pregnant sheep.
1/2021	Pharmacokinetics of buprenorphine in pregnant sheep after intravenous injection.

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Merja Kokki Research Topics

Disease

26	Pain (Aches) 01/2024 - 01/2010
12	Postoperative Pain 02/2024 - 05/2012
7	Neoplasms (Cancer) 01/2020 - 05/2016
6	Acute Pain 05/2022 - 05/2012
6	Wounds and Injuries (Trauma) 01/2020 - 05/2012
5	Hypoxia (Hypoxemia) 11/2021 - 01/2019
3	Alzheimer Disease (Alzheimer's Disease) 03/2021 - 05/2016
3	Cataract (Cataracts) 04/2016 - 01/2013
2	Hypotension (Low Blood Pressure) 01/2023 - 05/2012
2	Opioid-Related Disorders (Opiate Addiction) 11/2022 - 01/2021
2	Placental Insufficiency 11/2021 - 01/2019
2	Infections 01/2020 - 11/2018
2	Bacterial Infections (Bacterial Infection) 01/2020 - 01/2018
2	Neuroblastoma 06/2016 - 01/2016
2	Fever (Fevers) 01/2010 - 01/2010
1	Osteoarthritis 12/2023
1	Premature Birth (Birth, Premature) 09/2023
1	Stillbirth 09/2023
1	Respiratory Insufficiency (Respiratory Failure) 12/2021
1	Body Weight (Weight, Body) 12/2021
1	Lung Diseases (Lung Disease) 05/2021
1	Normal Pressure Hydrocephalus 03/2021
1	Breakthrough Pain 01/2021
1	Vomiting 08/2020
1	Nausea 08/2020
1	Pneumonia (Pneumonitis) 01/2020
1	Acute Kidney Injury (Acute Renal Failure) 09/2018
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018
1	Acidosis 02/2017
1	Asphyxia (Suffocation) 02/2017
1	Opioid-Induced Constipation 01/2017
1	Constipation 01/2017
1	Dementia (Dementias) 01/2017
1	Bullous Pemphigoid (Pemphigoid) 01/2017
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2017
1	Cognitive Dysfunction 01/2017
1	Inflammation (Inflammations) 06/2016
1	Memory Disorders (Memory Loss) 05/2016
1	Shoulder Pain 11/2015

Drug/Important Bio-Agent (IBA)

14	Oxycodone (Oxycontin)FDA LinkGeneric 02/2024 - 05/2012
14	Opioid Analgesics (Opioids)IBA 01/2023 - 09/2012
10	Analgesics (Analgesic Drugs)IBA 01/2024 - 01/2010
10	Biomarkers (Surrogate Marker)IBA 03/2021 - 05/2016
4	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2024 - 01/2010
4	Buprenorphine (Subutex)FDA LinkGeneric 12/2023 - 01/2021
3	Fentanyl (Sublimaze)FDA LinkGeneric 01/2021 - 09/2015
3	ProcalcitoninIBA 01/2020 - 01/2018
3	Morphine (MS Contin)FDA LinkGeneric 06/2016 - 05/2012
2	Nifedipine (Adalat)FDA LinkGeneric 11/2021 - 01/2020
2	Sufentanil (Sufenta)FDA LinkGeneric 08/2020 - 01/2017
2	3-nitrotyrosineIBA 01/2020 - 03/2019
2	Sildenafil Citrate (Viagra)FDA Link 01/2020 - 01/2019
2	CatalaseIBA 01/2020 - 11/2018
2	AutoantibodiesIBA 01/2018 - 01/2017
2	Naloxone (Narcan)FDA LinkGeneric 01/2017 - 05/2012
2	dexketoprofen trometamol (Keral)IBA 07/2016 - 12/2015
2	C-Reactive ProteinIBA 06/2016 - 05/2016
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 11/2015 - 01/2010
2	Ketoprofen (Orudis)FDA LinkGeneric 01/2010 - 01/2010
2	AntipyreticsIBA 01/2010 - 01/2010
1	TabletsIBA 02/2024
1	Tramadol (K315)FDA LinkGeneric 01/2024
1	Lactic Acid (Lactate)FDA LinkGeneric 11/2021
1	Oxygen (Dioxygen)IBA 05/2021
1	Hydromorphone (Dilaudid)FDA LinkGeneric 07/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2020
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019
1	Vasodilator Agents (Vasodilators)IBA 01/2019
1	Cystatin CIBA 09/2018
1	Lipocalin-2IBA 09/2018
1	Immunoglobulin G (IgG)IBA 01/2017
1	AutoantigensIBA 01/2017
1	Glutathione PeroxidaseIBA 01/2017
1	EtoricoxibIBA 07/2016
1	Interleukin-10 (Interleukin 10)IBA 06/2016
1	CytokinesIBA 06/2016
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 06/2016
1	InterleukinsIBA 06/2016
1	Interleukin-8 (Interleukin 8)IBA 06/2016
1	Interleukin-6 (Interleukin 6)IBA 06/2016
1	Non-Narcotic Analgesics (Analgesics, Non Narcotic)IBA 11/2015

Therapy/Procedure

12	Analgesia 05/2022 - 11/2015
5	Laparotomy 01/2020 - 02/2018
3	Pain Management 01/2024 - 01/2013
2	Epidural Analgesia 05/2022 - 03/2014
2	Therapeutics 05/2021 - 01/2020
2	Laparoscopic Cholecystectomy 12/2012 - 05/2012
1	Transdermal Patch 12/2023
1	Obstetric Surgical Procedures 09/2023
1	Gynecologic Surgical Procedures (Gynecologic Surgery) 01/2022
1	Anesthesia 10/2021
1	Patient-Controlled Analgesia (Analgesia, Patient Controlled) 02/2018
1	Arthroplasty 07/2016
1	Intravenous Administration 06/2016
1	Ophthalmologic Surgical Procedures 04/2016
1	Phacoemulsification 02/2016
1	Intraocular Lens Implantation 02/2016
1	Epidural Blood Patch 11/2015
1	Injections 11/2015